PTSD

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PTSD

1.) Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety‐related and substance abuse disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595771/

“Importantly, CBD produces an enduring reduction in learned fear expression when given in conjunction with fear memory reconsolidation or extinction by disrupting the former and facilitating the latter. This makes CBD a potential candidate for testing as a pharmacological adjunct to psychological therapies or behavioural interventions used in treating PTSD and phobias.”

2.) Cannabidiol Regulation of Learned Fear: Implications for Treating Anxiety-Related Disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121237/

“The evidence indicates that cannabidiol reduces learned fear in different ways: (1) cannabidiol decreases fear expression acutely, (2) cannabidiol disrupts memory reconsolidation, leading to sustained fear attenuation upon memory retrieval, and (3) cannabidiol enhances extinction, the psychological process by which exposure therapy inhibits learned fear. We also present novel data on cannabidiol regulation of learned fear related to explicit cues, which indicates that auditory fear expression is also reduced acutely by cannabidiol.”

3.) Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101100/

“The main finding from this case study is that CBD oil can be an effective compound to reduce anxiety and insomnia secondary to PTSD.”

4.) Cannabidiol as a Potential Treatment for Anxiety Disorders

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604171/

“Two studies were identified, including an uncontrolled retrospective study in civilian patients with PTSD patients [120], and a case study in a patient with severe sexual abuse-related PTSD [121], which showed that chronic cannabis use significantly reduces PTSD symptoms; however, these studies did not include data on the THC:CBD ratio. Thus, overall, no outcome data are currently available regarding the chronic effects of CBD in the treatment of anxiety symptoms, nor do any data exist regarding the potential protective effects of CBD on anxiety potentially induced by chronic THC use.”

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